THREE CHANGES TO ENGLAND STARTING TEAM

England has made three changes to its starting XV for the Italy game on Sunday. Ben Youngs replaces Care, Mako Vunipola replaces Marler and Courtney Lawes replaces Launchbury. All three drop to the bench, and will be joined by Maro Itoje, who is poised to make his international debut. England has never lost to Italy in 21 contests, although has come close a few times, and Parisse, running out of years, will be desperate to add an England scalp before he retires.

Itoje set to make his full international debut on Sunday

England starting team to face Italy:

Mike Brown (vice captain, Harlequins); Anthony Watson (Bath), Jonathan Joseph (Bath), Owen Farrell (vice captain, Saracens), Jack Nowell (Exeter Chiefs); George Ford (Bath), Ben Youngs (Leicester Tigers); Mako Vunipola (Saracens); Dylan Hartley (captain, Northampton Saints), Dan Cole (Leicester Tigers); Courtney Lawes (Northampton Saints), George Kruis (Saracens); Chris Robshaw (Harlequins), James Haskell (Wasps), Billy Vunipola (vice captain, Saracens).

Replacements: Jamie George (Saracens), Joe Marler (Harlequins), Paul Hill (Northampton Saints), Joe Launchbury (Wasps), Maro Itoje (Saracens), Jack Clifford (Harlequins), Danny Care (Harlequins), Alex Goode (Saracens).